• It has been suggested that the suppression

  2024-05-10

  

  It has been suggested that the suppression of 5-LOX could promote apoptotic signaling pathways in cancers [6]. However, the role of 5-LOX in modulating apoptotic factors and neutrophil activation during ANP has not yet been evaluated. In this study, we aimed to evaluate the expression of 5-LOX in pa

• br Material and methods br Results

  2024-05-10

  

  Material and methods Results Discussion Clinical gene therapy trials with viral vectors have been in use for treatment of various genetic disorders and diseases, however efficacious, targetable and highly reliable non-viral delivery systems are needed for safe and long-term applications. De

• 832 582 4016 br Studies in zebrafish vascular and neural dev

  2024-05-10

  

  Studies in zebrafish: vascular and neural development and the regulation of left–right asymmetry Zebrafish embryos represent an excellent model system to examine vertebrate vascular development. Major advantages of the zebrafish system include its genetic tractability, small size, external fertil

• br Role of autophagy in alcoholic

  2024-05-10

  

  Role of autophagy in alcoholic cardiomyopathy Concluding remarks The genetic and phenotypic heterogeneity in alcoholic cardiac injury has been recognized despite the seemingly beneficial effects of low to moderate alcohol consumption [8]. Although oxidative stress is well established in the pa

• Introduction The first use of the term autophagy by a

  2024-05-10

  

  Introduction The first use of the term “autophagy” by a French physiologist, M. Anselmier, in a short article describing the effects of fasting in mice published in 1859, took place almost a century before Christian De Duve described it from a mechanistic point of view in a symposium on lysosomes i

• br Results br Discussion br Conclusion The flux of

  2024-05-10

  

  Results Discussion Conclusion The flux of glucose into cytosolic short chain acyl-CoAs was maintained in pure beta Eribulin mesylate in the presence of inhibition of ATP citrate lyase with hydroxycitrate and also in a cell line with >90% ATP citrate lyase knockdown suggesting that a pathwa

• Human lipoxygenase exists in two forms named LOX also named

  2024-05-10

  

  Human 15-lipoxygenase exists in two forms, named 15-LOX-1 (also named 12/15-LOX, 15-LO-1) and 15-LOX-2. Several reports indicate that 15-LOX-1 has a pathophysiological role in respiratory inflammatory diseases, in particular asthma. Increased activity of 15-LOX-1 is displayed in the respiratory trac

• There are two major isoforms of LO in mammalian

  2024-05-10

  

  There are two major isoforms of 12/15-LO in mammalian, 12 and 15- LO, with different cellular distributions. To determine the relative contributions of these isoforms towards glucose-induced monocyte-endothelial interactions, the distribution of these isoforms in the two cell types involved in leuko

• Although the interactions of PhLP

  2024-05-10

  

  Although the interactions of PhLP with Gβγ and its other partners have been convincingly documented through in vitro studies, it is not clear how PhLP controls tgx receptor signaling in vivo. C. elegans provides a powerful genetic model to analyze Phosducin function and study its interacting partner

• The radiographic correlate will be similarly important for t

  2024-05-10

  

  The radiographic correlate will be similarly important for the success of other non-VEGF TKIs, such as those targeting the epidermal growth factor receptor expressed in 50% of high-grade primary 5-alpha reductase inhibitors neoplasms. It has been reported that icotinib and gefitinib, epidermal grow

• Although it is not known if

  2024-05-10

  

  Although it is not known if CP-AMPAR regulation is required for LTD, our previous characterization of AKAP150ΔPIX knockin mice that are selectively deficient in CaN anchoring, due to disruption of a PxIxIT-type CaN docking motif, provided important insights. We found that AKAP-CaN signaling dephosph

• LOXs and CYPs are a series of

  2024-05-10

  

  LOXs and CYPs are a series of iron-containing enzymes that metabolize arachidonic droperidol receptor to form biologically active products, such as epoxyeicosatrienoic acids (EETs) hydroperoxyeicosatetraenoic acids (HETEs), prostaglandins, leukotrienes and thromboxanes [6]. Among these mediators, 12

• Several enzymes in serine and glycine

  2024-05-10

  

  Several enzymes in serine and glycine metabolism have been proposed as biomarkers for cancer stage and prognosis. Phosphoglycerate dehydrogenase (PHGDH), phosphoserine phosphatase (PSPH), and serine hydroxymethyltransferase (SHMT) levels are high in TNBC and low in luminal-A breast cancers (Kim et a

• rxr receptor Active SI behavior was dose dependently affecte

  2024-05-09

  

  Active SI behavior was dose-dependently affected by PACAP treatment (F3,25 = 14.42, p rxr receptor 1 week later (F3,20 = 8.93, p hypothesis that PACAP causes disruptions in posterror adjustments that are similar to disruptions seen in humans with depression.

• br Acknowledgments and Disclosures br

  2024-05-09

  

  Acknowledgments and Disclosures Introduction In mammals, ejaculated sperm requires a finite period of residence in the female reproductive tract to become competent for fertilization (Visconti et al., 1995a, Visconti et al., 1995b). Once oocytes are matured, it is important for these cells to

14939 records 104/996 page Previous Next First page 上5页 101102103104105 下5页 Last page