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br Conclusions br Acknowledgments br
2023-11-04
Conclusions Acknowledgments Introduction To die or not to die – that is the question. Christian de Duve created the word “autophagy” in 1960’s for the first time (Klionsky et al., 2016). The word “autophagy” was derived from the Greek roots “auto” (self) and “phagy” (eating) and referred t
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br Conflict of interest statement
2023-11-04
Conflict of interest statement Funding Acknowledgments We thank the team at Medical and Collider-Accelerator Departments at BNL and for their support at NSRL. We thank Dr. Janice Pluth and Professor Peter O’Neill for useful discussions related to our work. Introduction The DNA damage re
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br Conflicts of interest br Introduction Photodynamic Therap
2023-11-04
Conflicts of interest Introduction Photodynamic Therapy (PDT) is a technique used for the treatment of several malignant and non malignant diseases (Akimoto, 2016, Keyal, Bhatta, Wang, 2016, Morton, Szeimies, Sidoroff, Wennberg, Basset-Seguin, Calzavara-Pinton, Gilaberte, Hofbauer, Hunger, Kar
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Kim et al found that hydroxydopamine OHDA promoted the
2023-11-04
Kim et al. (2013) found that 6-hydroxydopamine (6-OHDA) promoted the atrophy of dopaminergic neurons associated with the activation of poly (ADP-ribose) polymerase (PARP), the translocation of apoptosis inductor factor (AIF) and the depletion of ATP. An increase in p-AMPK and pS6K (upstream kinase o
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What is the mechanism by which Wnt a
2023-11-04
What is the mechanism by which Wnt7a-Fz7 signaling enhances AMPAR localization and synaptic strength? Following induction of LTP, the number of AMPARs rapidly increases at extrasynaptic sites (Makino and Malinow, 2009, Yang et al., 2008a) through PKA-dependent phosphorylation of GluA1 at S845 (He et
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amiodarone hcl receptor What is the mechanism by which Wnt a
2023-11-04
What is the mechanism by which Wnt7a-Fz7 signaling enhances AMPAR localization and synaptic strength? Following induction of LTP, the number of AMPARs rapidly increases at extrasynaptic sites (Makino and Malinow, 2009, Yang et al., 2008a) through PKA-dependent phosphorylation of GluA1 at S845 (He et
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Recently rather than predicting categorical variables as in
2023-11-04
Recently, rather than predicting categorical variables as in classification, several studies begin to estimate continuous clinical variables from OSI-420 synthesis images. Therefore, instead of classify a subject into binary or multiple pre-determined categories or stages of the disease, regression
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A clear link between ADR stimulation and
2023-11-04
A clear link between α2-ADR stimulation and decreased respiration in β-cells is established and consistent with proteomics data. Current discoveries in islets have identified physical interactions between ADR-coupled G proteins and cellular components such as insulin vesicles and ion channels (Zhao
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clodronate australia br Materials and methods br Results The
2023-11-04
Materials and methods Results The average body weights for each group of mice over the course of the study are shown in Fig. 2A. The average body weights of the mice in the saline control group and PACAP group increased slightly during the study. In contrast, starting at day 17, the body weigh
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br Therapeutic advantages and clinical
2023-11-04
Therapeutic advantages and clinical implications of caffeine treatment in ROP The demonstration of the role of the adenosine receptor in development of ROP and protection by caffeine suggests two potential therapeutic strategies with high translational potential: a) modification of caffeine treat
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It has been reported that leukotrienes and their
2023-11-03
It has been reported that leukotrienes and their receptors, e.g. the cysteinyl leukotriene receptor 1 (CysLT1) may promote Pam3CSK4 Biotin injury (Ding et al., 2007) and that increased 5-LOX expression and activity lead to production of brain-toxic molecules (Khan et al., 2010). However, differenti
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br Dihydrotestosterone in adult fish and
2023-11-03
Dihydrotestosterone in adult fish and frogs New perspectives and next directions Similar to other androgens, DHT can modulate reproductive endpoints in both fish and amphibians. However, predicting the effects of DHT can be challenging, as reproductive homeostasis is dependent upon the balance
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br Introduction The process of mitosis
2023-11-03
Introduction The process of mitosis is highly complex and tightly regulated. This phase of the tlr inhibitor resulted in two identical daughter cells. The aurora kinases (aurora A, B, and C) are a family of three highly homologous serine-threonine protein kinases that play a key role in regulati
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Thirdly and finally multiple studies have analyzed
2023-11-03
Thirdly and finally, multiple studies have analyzed the activation of neurons in the auditory telencephalic areas of songbirds in response to various auditory stimuli. Neuronal activation was identified by the increased expression of immediate early genes such as fos or ZENK (also know as zif-268, e
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br Introduction Endothelial progenitor cells EPCs present
2023-11-03
Introduction Endothelial progenitor cells (EPCs) present a class of blood cells with an ability to form new blood vessels relying on pre-existing vessels, which contribute to postnatal angiogenesis [1], [2]. A wide range of studies have demonstrated that EPCs play a critical role in angiogenesis
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