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The Lyapunov exponent plays a key role in the
2020-03-02
The Lyapunov exponent, plays a key role in the spectral analysis of the family . Here, S denotes the so-called Szegő transfer matrix, defined by Because the matrices so defined satisfy for , we have for . We define By general considerations, there is a compact set with for μ-a.e. . Moreover, by
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It has been reported that NMDA receptor hypofunction upregul
2020-03-02
It has been reported that NMDA receptor hypofunction upregulates the expression of immediate early genes in several hcv virus regions [39], [40]. Consistent with this finding, we demonstrated that MK-801 increased the number of c-Fos-positive cells in the PVN and PC/RS (Fig. 5). Importantly, the MK
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In we studied normal rational varieties
2020-03-02
In [1] we studied normal, rational -varieties X of complexity one, where the latter means that X comes with an effective torus action such that holds. We showed that for affine X with and at most log terminal singularities, the iteration of Cox rings is possible. In the present article, we character
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br Introduction Ewing s sarcoma
2020-03-02
Introduction Ewing’s sarcoma (ES) is a mesenchymal tumor characterized by small, round, blue cells, and is poorly differentiated and highly malignant [1]. While ES typically arises in bone and soft tissue, rare primary extraosseous manifestations of ES have been reported throughout the body [2].
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br Author contribution br Acknowledgements We want to thank
2020-03-02
Author contribution Acknowledgements We want to thank Dr. Manuel Rodriguez, Dr. Ch. Blattner, Dr. Jorge Moscat, Dr. Erwin Knecht and Dr. Peter Tontonoz for materials. This work has been supported by grants from the Spanish Ministry of Education and ScienceSAF2011-27442 and a grant from General
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CD is a key co stimulation surface
2020-02-28
CD28 is a key co-stimulation surface marker that can be detected in all peripheral T ACY-241 in newborns, and the proportion of CD28bearing T cells reduces progressively with age [reviewed by (Fagnoni et al., 1996; Weng et al., 2009)]. Therefore, CD28nullCD8+ T cells are one of the most acknowledge
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Despite many studies having demonstrated the importance of c
2020-02-28
Despite many studies having demonstrated the importance of connexin43 (Cx43), the most abundant connexin in bone cells, for bone development and turnover during the last decade [27], little is currently known about GJIC and Cx43 in primary bone tumors. In this report, we analyzed the specific role o
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Recoverin is a kDa retinal protein that binds to calcium
2020-02-28
Recoverin is a 23-kDa retinal protein that binds to calcium. It regulates the BIIE 0246 of rhodopsin during visual transduction within photoreceptor cells. Since the pathogenicity of anti-recoverin antibody is potent, anti-recoverin CAR patients often have progressive visual impairments, characteri
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We also determined the uracil content of CJ
2020-02-28
We also determined the uracil content of CJ236 DNA by thin-layer chromatography of in vivo32P- or [6-3H]uracil-labeled CJ236 2′-deoxyribose 5′-monophosphates as well as by LC/MS of deoxyuridine and thymidine 2′-deoxynucleosides (Table 1, Table 2, Table 3). Examination of the 32P data showed that, ba
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In these studies the inflammatory cytokine
2020-02-28
In these studies, the inflammatory cytokine IL-8 was demonstrated as one of the responsible molecules induced by CysLTs via activating CysLT2 receptors. IL-8 is synthesized in and released from mononuclear cells, macrophages, fibroblasts and airway epithelial cells, and it promotes inflammation as a
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For in vitro expression analysis of CXCL and CXCRs by
2020-02-28
For in vitro expression analysis of CXCL8 and CXCRs by stimulated leucocytes, peripheral blood leucocytes (PBLs) were isolated using Percoll density gradient centrifugation as described earlier . Cell suspensions were adjusted to 5×10/ml. Four milliliters of tissue culture medium were plated per wel
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br Development of a liquid chromatography mass
2020-02-28
Development of a liquid chromatography-mass spectrometry method to improve detection of PA species detection Liquid chromatography-mass spectrometry (LC-MS) is a powerful tool to detect different molecular species of phospholipids in YM 58483 (Houjou et al., 2005, Pulfer and Murphy, 2003). Howev
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516 3 In this study we have developed and investigated three
2020-02-28
In this study we have developed and investigated three NADPH-regenerating fusion partners with two different enzyme systems: a BVMO and an ADH. With the exception of one fusion construct (StGDH with LbADH), all fusion 516 3 resulted in good soluble expression as well as fully functional as self-suf
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The proliferation of CCA cell
2020-02-28
The proliferation of CCA cell lines can be stimulated by estrogen and other growth factors (Alvaro et al., 2006; DeMorrow, 2009; Mancino et al., 2009). It has also been reported that estrogen positively modulates cholangiocyte proliferation, which is associated with cholangiopathies found in humans
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br Results br Discussion The nitric oxide cyclic guanosine m
2020-02-28
Results Discussion The nitric oxide-cyclic guanosine monophosphate pathway plays an important role in normal EF, and oral PDE-5Is were developed in the late 90s after the discovery that ED occurs when there is a problem with this pathway. Since then, several PDF-5Is with different pharmacokine
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