• br Disclaimer Statement br Acknowledgments br Introduction M

  2025-01-27

  

  Disclaimer Statement Acknowledgments Introduction Metabolic changes are a common feature of cancerous tissues. Mutations in oncogenes and tumor suppressor genes cause alterations to multiple intracellular signaling pathways that rewire tumor cell metabolism and re-engineer it to allow enhan

• (+)- Corydaline br ACL Regulation and Role in Lipid Metaboli

  2025-01-27

  

  ACL Regulation and Role in Lipid Metabolism ACL is a ubiquitous enzyme at the nexus of nutrient catabolism and synthesis of cholesterol and fatty acids. In mammals, it is highly expressed in lipogenic tissues including adipose, liver, and lactating mammary glands [9]. In the presence of ATP and C

• Recently dairy proteins obtained from whey have received con

  2025-01-27

  

  Recently, dairy proteins obtained from whey have received considerable attention for their antioxidant bioactivity (Bayram et al., 2008; Haraguchi et al., 2011; Zhang et al., 2012). Bovine whey proteins (WP) are widely used in various foods for their nutritional, health-promoting, and functional val

• Introduction Enzymatic browning degrades quality safety and

  2025-01-27

  

  Introduction Enzymatic browning degrades quality, safety, and nutritional values of various fruits or vegetable products. For example, the color of apple or potato is generally yellowish, representing freshness. However, they are extremely susceptible to enzymatic browning because of abundant polyp

• br Methodology br Antibiotics in lakes br Antibiotic resista

  2025-01-27

  

  Methodology Antibiotics in lakes Antibiotic resistance genes in lakes Perspectives of study on l glycine and ARGs in lakes Conclusion This paper systematically reviewed the distribution of antibiotics and ARGs in global lakes. A total of 57 antibiotics reported at least once in the w

• It has been proposed that angiotensin

  2025-01-27

  

  It has been proposed that angiotensin II (Ang II) may upregulate COX-2 expression and the subsequent vasoconstrictor prostanoids production through the activation of AT-1 receptors in vascular smooth muscle cells (Hu et al., 2002). Additionally, this peptide is also able to stimulate the generation

• br Introduction Heart Failure HF is a

  2025-01-27

  

  Introduction Heart Failure (HF) is a major and growing health challenge in India and the developing countries. It is one of the most important causes of morbidity and mortality in the industrialized world. The incidence and prevalence estimates of HF are unreliable in India because of the lack of

• Introduction Cardiovascular disease is the principal cause o

  2025-01-27

  

  Introduction Cardiovascular disease is the principal cause of morbidity and mortality in patients with Desformylflustrabromine hydrochloride receptor (1). Comprehensive management of these patients includes not only adequate glycemic control but also attention to additional recognized risk factors

• The chronic induction of skeletal muscle

  2025-01-27

  

  The chronic induction of skeletal muscle AMPK activity is an attractive therapeutic approach for DMD, as it addresses multiple cellular pathways needed for powerful phenotypic plasticity, including activation of the slow oxidative myofiber program, corrective autophagic signaling, as well as regulat

• br Results br Discussion By using an unbiased proteomic

  2025-01-27

  

  Results Discussion By using an unbiased proteomic screen for xCT binding partners, followed by functional validation, we have made the surprising discovery that mTORC2 regulates amino 2-D08 metabolism in tumor cells by phosphorylating serine 26 of the cystine-glutamate antiporter xCT on its cy

• Our in vitro data show that CyaA does not play

  2025-01-26

  

  Our in vitro data show that CyaA does not play a critical role in the bacterial adherence to mammalian cells. This observation is in contrast to previous studies that reported a role for CyaA in FHA-mediated adherence of B. pertussis bacteria to the respiratory epithelial vasopressin receptor antago

• br Acknowledgments This work was supported by

  2025-01-26

  

  Acknowledgments This work was supported by the R&D Program of the Institutional Research Program of KRICT (SI1701-02), and by the Next generation carbon upcycling project of Ministry of Science and ICT. JSC is kindly grateful to the National Research Council of Science and Technology (NST) for fi

• CYP A is one of the

  2025-01-26

  

  CYP3A4 is one of the key metabolizing 6-Hydroxydopamine hydrobromide of the cytochrome P450 (CYP) superfamily of heme-containing monooxygenases. As the CYP family of enzymes plays important roles not only in the xenobiotic metabolism and detoxification of a large number of drugs, but also in the bi

• Our outcrossing data confirmed that ACL

  2025-01-26

  

  Our outcrossing data confirmed that ACL1 and ACL2 have important temporal and spatial functions in ascospore delimitation in G. zeae. When each ACL deletion mutant was used as male for outcrossing, nuclear division and spore delimitation were not properly progressed in most asci. Ascospores that con

• br Mechanisms of GPCR internalization Like

  2025-01-26

  

  Mechanisms of GPCR internalization Like for other types of receptors, prolonged agonist stimulation often leads to GPCR internalization, which can occur via different pathways ∗[2], [20], [21], [22], [23]. Of these pathways, clathrin-mediated NNC 55-0396 (CME) is the best characterized and argua

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