• br Results br Discussion Prostate cancer dissemination and s

  2021-07-08

  

  Results Discussion Prostate cancer dissemination and skeletal metastases represent major therapeutic challenges. Once the skeletal metastasis occurs, the incurable patient could just be symptomatically treated to alleviate the pain. Therefore it is of great necessity to disclose the molecular

• br Results and Discussion br Conclusions Based on their comm

  2021-07-08

  

  Results and Discussion Conclusions Based on their common NTP pyrophosphatase activity, similar size of the catalytic domains, and the conservation of glutamate residues, it was assumed previously that the MazG and HisE families were related to MutT and other Nudix family hydrolases (see Zhang

• Pathological changes in animal are powerful indicators of th

  2021-07-08

  

  Pathological changes in animal are powerful indicators of the exposure to environmental stressors. The liver serves as an appropriate organ for the study of pollutant effects because of its high capacity to accumulate pollutant and its susceptibility to histopathological damage by pollutants (Padmin

• br Neuroimaging Neuroimaging has not yet been systematically

  2021-07-08

  

  Neuroimaging Neuroimaging has not yet been systematically reported in individuals with CDD, although case reports document normal amiodarone hcl anatomy or less often, show cortical atrophy or T2 fluid-attenuated inversion recovery hyperintensities in the white matter.15, 17, 18, 19, 48, 52, 54,

• We next examined the effects

  2021-07-08

  

  We next examined the effects of substituents around the carboxylic CBiPES hydrochloride moiety on CRTH2 binding (Table 4). The carboxylic acid moiety shared by the representative CRTH2 antagonists and is essential for the CRTH2 activity. Germinal dimethylation of the methylene moiety next to the car

• br Methods br Results br Discussion On the other

  2021-07-08

  

  Methods Results Discussion On the other hand, surgical patients have to some extent stress during pre- and/or post-operative period. It is well known that CRF/CRF1 receptor is involved in the activation of HPA during acute and chronic stress (Papadimitriou and Priftis, 2009, Zelena et al.,

• 9-Phenanthrol br Tests and measurements We used a

  2021-07-08

  

  Tests and measurements We used a set of FPGA cores for all tests and measurements. Firstly, the control circuit for the Controlled Current Limiter illustrates the proposed TMR method. The circuit contains a D-Register to enable or disable the power to the protected device, a counter, which is use

• br Materials and methods br Results

  2021-07-08

  

  Materials and methods Results and discussion Iron (II)/2-oxoglutarate (2-OG)-dependent oxygenases [28], [29] catalyze oxidative reactions of a range of metabolic processes including the hydroxylation of l-proline and l-lysine residues during the post-translational modification of collagen. Mor

• RCT pathway plays a critical role in

  2021-07-08

  

  RCT pathway plays a critical role in the maintenance of cholesterol homeostasis by facilitating the cholesterol clearance and cholesterol efflux (Levinson & Wagner, 2015). In the process of RCT, ABCA1 and ABCG1 played as crucial regulators in cholesterol efflux (Yasuda et al., 2011). Compared with h

• Cell swelling stimulates the release

  2021-07-08

  

  Cell swelling stimulates the release of certain amino acids, in particular the non-protein amino Decanoyl-RVKR-CMK synthesis taurine, via a pathway which has the characteristics of a channel rather than a carrier [54], [69]. Indeed, on the basis of pharmacological inhibition, it was suggested that v

• br Materials and methods br Results

  2021-07-08

  

  Materials and methods Results Discussion We have evaluated the breast cancer prevention potential of PR blockade under conditions that included exposure to progestogens that are relevant to women (progesterone and MPA) and are known to differ in their receptor-binding and down-stream effect

• br Materials and methods br Results br Discussion The

  2021-07-08

  

  Materials and methods Results Discussion The main finding of the present study is that selective ETA and dual ETA/ETB receptor blockade markedly improve endothelium-dependent vasodilatation in patients with type 2 diabetes and vascular complications. The magnitude of improvement did not dif

• br Author Contributions br Acknowledgments This work was sup

  2021-07-08

  

  Author Contributions Acknowledgments This work was supported, in part, by a grant from the National Cancer Institute of the National Institutes of Health under Grant U01CA202241 and National Institutes of Health under Grant R01NS083856. Introduction The Eph (erythropoietin-producing human

• br Experimental Procedures br Acknowledgments We thank R

  2021-07-07

  

  Experimental Procedures Acknowledgments We thank R. Brink for providing HEL2x, M. Tanaka for CD169DTR mice, R. Lathe for making Cyp7b1+/− mice available, and M. Barnes and A. Reboldi for comments on the manuscript. T.Y. is an Irvington Institute Postdoctoral Fellow at the Cancer Research Insti

• E is a classical initiator

  2021-07-07

  

  E1 is a classical initiator protein and, as such, plays several roles in the initiation and catalysis of viral DNA synthesis. E1 must first recognize a specific segment of the viral Caspase-3/7 Inhibitor known as the “origin of DNA replication”, or “ori” for short. For most PV types examined to date

15685 records 605/1046 page Previous Next First page 上5页 601602603604605 下5页 Last page