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br Materials and methods br Results br
2020-12-16
Materials and methods Results Discussion Plg plays important roles in various physiological processes, such as fibrinolysis, proteolysis, cell migration, differentiation, tissue remodeling, and inflammation [6], [7], [8]. We herein found that Plg deficiency enhanced insulin secretion, and w
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DSBs can be repaired by
2020-12-16
DSBs can be repaired by two major pathways: canonical non-homologous end-joining (c-NHEJ) and homologous recombination (HR) (Chapman et al., 2012). c-NHEJ comprises two sub-pathways, a resection-independent process and a resection-dependent process, and can rejoin break ends with little or no sequen
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br Introduction In most of the angiosperms sexual reproducti
2020-12-16
Introduction In most of the angiosperms, sexual reproduction requires a process called double fertilization where the specialized cell division called meiosis produces haploid gametes combine to form diploid (2n) embryo. In adenosine antagonist to this, apomixis, naturally occurs in at least 400
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The methods for DNA MTase activity
2020-12-16
The methods for DNA MTase activity assay involve radioactive labelling [15], gel electrophoresis [16], high-performance liquid chromatography [17], [18], bisulfite conversion [19], [20], and affinity enrichment [21], [22]. In these methods, the methylated bases under the action of active MTase could
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Most of the amino acid residues contacting
2020-12-16
Most of the amino 4-Aminobutyric acid sale residues contacting the substrate are within the nucleotide-recognition lid (mauve or magenta in Fig. 4A). Two particularly important residues, W69 and Y76, are conserved in eubacteria and in some but not all of eight human AlkB homologs [52], [76] (Fig. 4
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Introduction BRs are well known class of steroid
2020-12-16
Introduction BRs are well known class of steroid phytohormones involved in the regulation of key processes of plant growth and development [1], [2], [3], [4], [5]. A lot of attention is driven to BRs in the last decade because of their undeniable functions in promoting Memantine hydrochloride rea
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Analysis of Table shows that compound b in which
2020-12-16
Analysis of Table 1 shows that compound 7b, in which the biphenyl scaffold does not bear any substituent, displays its inhibitory potency in the micromolar range (IC50 = 11 μM). If the amide bridge is moved from position 1 to 3 of the biphenyl system, product 7c is yielded, whose potency is about 4
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The p controls transcription of several genes that affect
2020-12-16
The p53 controls transcription of several genes that affect the release of cytochrome c in the mitochondrial apoptotic pathway [44]. In addition, p53 can induce a transcription-independent apoptosis through a direct interaction with the Bcl-2 family proteins [45]. However, the role of mitochondrial
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Collagen X is a homotrimeric molecule of three X chains
2020-12-16
Collagen X is a homotrimeric molecule of three α1(X) chains (Mr 59 kDa) comprising a 45 kDa triple-helical domain flanked by an N-terminal (NC2) and a larger C-terminal (NC1) non-collagenous domains (Shen, 2005). In the hypertrophic ECM, collagen X most likely forms an extended hexagonal network, as
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E cadherin is an adhesive Ca dependent
2020-12-16
E-cadherin is an adhesive Ca2+ dependent transmembrane protein mediating tight and strong cell-cell adhesion through homophilic interactions. There is strong evidence in favour of the major role of E-cadherin in melanocytes adhesion to keratinocytes in the SCR7 pyrazine sale (Tang et al., 1994). The
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Although elevated production of cysLTs is
2020-12-16
Although elevated production of cysLTs is characteristic of rhinosinusitis of diverse etiology, patients with aspirin-sensitive rhinosinusitis show even higher levels of cysLTs in the nasal mucosa, which are further enhanced by aspirin challenge., Elevated production of cysLTs in these patients may
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In the pleural exudates which reflect the in vivo
2020-12-16
In the pleural exudates, which reflect the in vivo conditions, the concentrations of CysLTs and PGE2 were quite similar. However, when cancer Nucleozin australia were cultured for 24 h, both analyses of cell culture medium and cell incubations with Ca2+ ionophore showed low levels of CysLTs. In cont
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br Materials and methods br Results br
2020-12-16
Materials and methods Results Discussion This study is the first to our knowledge that describes upstream cis-elements and transcription factors that are important for Crm1 expression and that drive its high expression in cancer and transformed cells. Using deletion and mutation analysis we
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Introduction Since the recognition of AIDS in more
2020-12-16
Introduction Since the recognition of AIDS in 1981 more than thirty-five years ago, nearly 70 million individuals have been infected with human immunodeficiency virus type 1 (HIV) and roughly half have died (http://www.unaids.org/en/resources/documents/2016/AIDS-by-the-numbers). Although the introd
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In general accurate results for
2020-12-16
In general, accurate results for the prediction of the solubility in scCO2 + cosolvents using the CPA-EoS were verified. ALD values for each solute (Table 1) varied from 0.04 to 1.5. Few solutes, such as lauric acid, myristic acid, hydroquinone and salicylic acid, presented the highest ALD values. A
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